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But for patients and clinicians weighing options, a framework helps

Desensitization Desensitization and tolerance are very similar in their definition as they both include the notion of a reduced response after prolonged treatment

antiinflammatory Both peptides help calm inflammation, though they do so through different processes in the body

JAMA 313 , 2263 (2015)

Metformin addresses hepatic glucose production while tirzepatide handles incretin-mediated insulin sensitization, appetite regulation, and weight management